Translational Neuroscience: Toward New Therapies
Edited by Karoly Nikolich and Steven E. Hyman
Published by MIT Press ISBN: 9780262029865
The Ernst Strüngmann Forum - PDF
1 - Introduction - PDF
Karoly Nikolich and Steven E. Hyman
Neurodevelopmental Disorders: A New Beginning
2 - What Do We Know about Early Onset Neurodevelopmental Disorders? - PDF
Thomas Bourgeron
3 - Psychotic Disorders and the Neurodevelopmental Continuum - PDF
Michael J. Owen
4 - Neurodevelopmental Disorders: What Is to Be Done? - PDF
Stephan Heckers, Steven E. Hyman, Thomas Bourgeron, Bruce N. Cuthbert, Raquel E. Gur, Cynthia Joyce, Andreas Meyer-Lindenberg, Michael J. Owen, and Matthew W. State
Neurodegenerative Diseases: Coming Unstuck
5 - Neurodegenerative Diseases: Where Are We Not Looking for Answers? - PDF
Walter J. Koroshetz and Lennart Mucke
6 - Preclinical and Clinical Understanding: Major Gaps in Our Understanding and Capabilities - PDF
Edward H. Koo
7 - Neurodegenerative Diseases: What Is to Be Done? - PDF
David M. Holtzman, Karoly Nikolich, Menelas N. Pangalos, Karl Broich, Nancy Y. Ip, Edward H. Koo, Walter J. Koroshetz, Eliezer Masliah, Lennart Mucke, Pierluigi Nicotera, Mareike Schnaars, and Maria Grazia Spillantini
New Tools to Drive Future Therapies
8 - How Might We Get from Genes to Circuits to Disease? - PDF
Tobias Kaiser, Yuan Mei, and Guoping Feng
9 - How Do We Define and Modulate Circuits in Animals That Are Relevant to Pathophysiology in Humans? - PDF
Joel S. Perlmutter
10 - Pathophysiological Toolkit: Genes to Circuits - PDF
Gül Dölen, Robert C. Malenka, Joel S. Perlmutter, Nils Brose, Richard Frackowiak, Bruce N. Cuthbert, Ilka Diester, Isabelle Mansuy, Katja S. Kroker, Tobias M. Boeckers, Alvaro Pascual-Leone, Guoping Feng
Living Systems: From Models to Patients
11 - Using a Stem Cell-Based Approach to Model Neurodegenerative Disease: Where Do We Stand? - PDF
Lee L. Rubin
12 - From Rodent Behavioral Models to Human Disorders - PDF
Trevor W. Robbins
13 - Bridging the Gap between Patients and Models - PDF
Ilka Diester, Franz Hefti, Isabelle Mansuy, Alvaro Pascual-Leone, Trevor W. Robbins, Lee L. Rubin, Akira Sawa, Marius Wernig, Gül Dölen, Steven E. Hyman, Lennart Mucke, Karoly Nikolich, and Bernd Sommer
Epilogue
14 - The Revolution Has Begun - PDF
Steven E. Hyman and Karoly Nikolich
Bibliography - PDF